Acetonitrile (anhydrous, 99.8%) is a high-purity organic solvent and intermediate used in moisture-sensitive organic synthesis, DNA/RNA synthesis, and specialized analytical applications.
Acetonitrile (CH₃CN) is a clear, colorless liquid and the simplest organic nitrile. This anhydrous grade is specifically processed to contain extremely low levels of water (≤10 ppm), making it essential for reactions where the presence of moisture can deactivate catalysts or degrade products. It is widely utilized as a solvent in pharmaceutical manufacturing, as a reagent in the synthesis of oligonucleotides, and as a medium for electrochemical studies due to its high dielectric constant and ability to dissolve a wide range of ionic and non-polar compounds. Its low chemical reactivity and excellent solvent properties make it a staple in advanced laboratory research.
Advantages
- Anhydrous grade with ultra-low water content (≤0.001%) for moisture-sensitive chemistry.
- High assay (≥99.8%) ensuring minimal interference from organic impurities.
- Excellent miscibility with water and most organic solvents.
- Suitable for peptide synthesis and other high-performance synthetic applications.
- Stable under standard laboratory conditions when stored correctly.
Technical specifications
| Catalogue number | 360457 |
| Product name | Acetonitrile |
| CAS Number | 75-05-8 |
| Molecular Formula | CH3CN |
| Molecular Weight | 41.05 g/mol |
| Assay (GC) | ≥99.8% |
| Water (KF) | ≤0.001% (≤10 ppm) |
| Boiling Point | 81–82 °C (lit.) |
| Density | 0.786 g/mL (25 °C) |
| Storage Temperature | Room temperature (15–25 °C) |
| Brand | Merck |