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360457 Acetonitrile, Merck

360457 Merck

Acetonitrile (anhydrous, 99.8%) is a high-purity organic solvent and intermediate used in moisture-sensitive organic synthesis, DNA/RNA synthesis, and specialized analytical applications.

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Acetonitrile (CH₃CN) is a clear, colorless liquid and the simplest organic nitrile. This anhydrous grade is specifically processed to contain extremely low levels of water (≤10 ppm), making it essential for reactions where the presence of moisture can deactivate catalysts or degrade products. It is widely utilized as a solvent in pharmaceutical manufacturing, as a reagent in the synthesis of oligonucleotides, and as a medium for electrochemical studies due to its high dielectric constant and ability to dissolve a wide range of ionic and non-polar compounds. Its low chemical reactivity and excellent solvent properties make it a staple in advanced laboratory research.

Advantages

  • Anhydrous grade with ultra-low water content (≤0.001%) for moisture-sensitive chemistry.
  • High assay (≥99.8%) ensuring minimal interference from organic impurities.
  • Excellent miscibility with water and most organic solvents.
  • Suitable for peptide synthesis and other high-performance synthetic applications.
  • Stable under standard laboratory conditions when stored correctly.

Technical specifications

Catalogue number 360457
Product name Acetonitrile
CAS Number 75-05-8
Molecular Formula CH3CN
Molecular Weight 41.05 g/mol
Assay (GC) ≥99.8%
Water (KF) ≤0.001% (≤10 ppm)
Boiling Point 81–82 °C (lit.)
Density 0.786 g/mL (25 °C)
Storage Temperature Room temperature (15–25 °C)

 

Brand Merck