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100042 Acetic anhydride EMSURE, Merck

100042 Merck

Acetic anhydride for analysis (EMSURE® ACS, ISO, Reag. Ph Eur) is a high-purity analytical reagent used as an acetylating agent in organic synthesis, pharmaceutical testing, and various analytical procedures.

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Acetic anhydride (CH₃CO)₂O is a colorless liquid with a strong, pungent odor. This EMSURE® grade product is meticulously tested to meet the requirements of the American Chemical Society (ACS), ISO standards, and the European Pharmacopoeia (Reag. Ph Eur). Its high purity and strictly controlled levels of impurities make it indispensable for quantitative analysis and quality control in the pharmaceutical industry. It is primarily used for the acetylation of alcohols, phenols, and amines, as well as in the determination of water by titration (e.g., in non-aqueous solvents) and the identification of various organic functional groups.

Advantages

  • Multicompliance with ACS, ISO, and Ph Eur standards for global regulatory consistency.
  • High assay (≥99.0%) ensures reliable performance in complex organic syntheses.
  • Low residue after evaporation and minimal levels of trace impurities (heavy metals, chloride, sulfate).
  • Part of the EMSURE® line, providing comprehensive documentation for audit-ready laboratory operations.
  • Strictly controlled color (≤10 Hazen) for use in sensitive spectrophotometric applications.

Technical specifications

Catalogue number 1.00042
Product name Acetic anhydride for analysis EMSURE®
CAS Number 108-24-7
Molecular Formula (CH3CO)2O
Molecular Weight 102.09 g/mol
Assay (alkalimetric) ≥99.0%
Density 1.08 g/cm³ (20 °C)
Boiling Point 139.5 °C (1013 hPa)
Flash Point 49 °C
Storage Temperature Room temperature (15–25 °C)

Available packaging options

1000421000 1 L 
1000422500 2.5 L
1000429025 25 L
Brand Merck