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803528 Diacetyl, Merck

803528 Merck

Diacetyl (2,3-Butanedione) for synthesis is a high-quality organic reagent used as a building block in chemical synthesis, specifically for the preparation of heterocyclic compounds and as a flavor/fragrance intermediate.

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Diacetyl is a vicinal diketone with the chemical formula (CH₃CO)₂. It is a yellowish to green liquid with a very intense, buttery odor. In synthetic chemistry, it is primarily used as a precursor for the synthesis of various nitrogen-containing heterocycles, such as quinoxalines and imidazoles, through condensation reactions with diamines. Due to its reactive dione structure, it also serves as a specialized ligand in coordination chemistry. This "for synthesis" grade ensures a high level of purity suitable for routine laboratory scale-up and industrial synthetic processes.

Advantages

  • High purity (≥98.0%) ensuring consistent yields in organic condensation reactions.
  • Versatile synthetic intermediate for the pharmaceutical and fragrance industries.
  • Excellent solubility in water, ethanol, and ether.
  • Strictly controlled physical properties (density, refractive index) for process reliability.
  • Reliable "for synthesis" quality suitable for academic research and industrial manufacturing.

Instructions for use

Diacetyl is a highly flammable liquid and should be handled away from heat, sparks, and open flames. It has a low flash point and a strong odor, so it must be used in a high-efficiency fume hood with appropriate personal protective equipment (nitrile gloves, safety goggles). It is sensitive to air and light; keep the container tightly sealed and store in a cool, dark place. For optimal stability, storage under an inert gas (nitrogen or argon) is recommended. Avoid contact with strong oxidizing agents and strong bases.

Technical specifications

Catalogue number 8.03528
Product name Diacetyl for synthesis
CAS Number 431-03-8
Molecular Formula C4H6O2
Molecular Weight 86.09 g/mol
Assay (GC) ≥98.0 %
Density 0.98 g/cm³ (20 °C)
Boiling Point 88 °C (1013 hPa)
Flash Point 7 °C
Storage Temperature 2–8 °C (Recommended)

Available packaging options

8035280002 2 mL glass bottle
8035280100 100 mL glass bottle 
8035280250 250 mL glass bottle
Brand Merck