The NucleoCounter® NC‑202™ is a high-precision, cassette-based cell counter designed for fast, accurate, and consistent cell counting and viability analysis. It delivers results in just 30 seconds and eliminates human error using the Via2-Cassette™ system. With a wide counting range, built-in DebrisIndex™, and 21 CFR Part 11/GMP-ready software, it's ideal for both research and GMP-compliant manufacturing environments.
The NucleoCounter® NC‑202™ is a third-generation, cassette-based automated cell counter designed for uncompromised precision and reliability in both research and production settings. Equipped with upgraded hardware and intuitive NC‑View™ software, it offers rapid, fluorescence-based image analysis in just ~30 seconds—eliminating manual bias. Thanks to dual fluorescence channels, it accurately quantifies cell number, viability, diameter, aggregation, and even culture debris via the new DebrisIndex™ feature. Its broad dynamic range (5 × 10⁴ to 1 × 10⁷ cells/mL) removes the need for dilutions, streamlining workflows. Fully compliant with 21 CFR Part 11/GMP, this scalable system suits applications from basic R&D to stringent GMP‑regulated QC and clinical environments. The closed-system Via2-Cassette™ minimizes human error and exposure to toxic reagents, making it ideal for high-containment, clinical, or manufacturing labs.
Advantages & Key Features
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Reproducible across users, instruments, and sites
Total inter-operator and instrument variability is kept within 5–10%, thanks to high-end optics and factory calibration. -
Eliminates human error
Use of the innovative Via2-Cassette™ ensures uniform sample prep—aspiration, staining, and loading are automated. -
Comprehensive culture health insights
The DebrisIndex™ quantifies residue accumulation, offering early alerts for culture quality issues. -
Extended counting range
Accurately measures up to 1 × 10⁷ cells/mL without dilution—a major time saver. -
GMP-grade software
NC‑View™ supports 21 CFR Part 11 compliance, secure data handling, and smooth deployment in regulated workflows. -
Safe, closed design
The self-contained cassette system removes pipetting, reagent exposure, and cleanup, enhancing operator safety and convenience.
Usage Recommendations
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Load Sample into Via2-Cassette™
Introduce ~60 µL of sample. The cassette automates aspiration, dye mixing, and chamber placement. -
Insert & Run
Drop the cassette into NC‑202, press RUN, and ~30 seconds later the instrument delivers output via NC‑View™. -
Review Data & Interpret DebrisIndex™
Analyze standard parameters and monitor the DebrisIndex™ to guide downstream processing decisions or detect potential contamination. -
Ensure GMP Readiness
Use NC‑View™ in compliance with 21 CFR Part 11 workflows. Perform IQ/OQ validation as needed (protocols included). -
Maintain System Hygiene
Dispose of used cassettes after each run. Clean the sample port occasionally to keep optics clear—refer to the user manual for details.
Technical Specifications
| Feature | Specification |
|---|---|
| Loading volume | ~60 µL into Via2-Cassette™ |
| Analyzed volume | 1.35 µL per cassette |
| Analysis time | ~30 seconds |
| Cell concentration | 5 × 10⁴ to 1 × 10⁷ cells/mL linear range |
| Dimensions (W×H×D) | 38 × 26 × 22 cm |
| Weight | 4.9 kg (10.8 lb) |
| Optics & imaging | ×2.1 magnification; 2/3″ CMOS sensor |
| Fluorescence | Dual LEDs: 365 nm & 505 nm; Emission filter 410–460 nm, 540–650 nm |
| Software | NC‑View™ (21 CFR Part 11/GMP compliant) |
| Brand | ChemoMetec |
