Breakthrough in Biomass Monitoring: Discover the OPTURA SPY® Sensor

A powerful new tool is now available to enhance real-time biomass monitoring across a wide range of bioprocesses: OPTURA SPY®—an innovative, contact-less sensor designed to deliver reliable, non-invasive measurements directly through the vessel wall.

Engineered with precision and practicality in mind, OPTURA SPY® sets a new standard for ease of integration and data clarity in both research and production environments. Developed by a trusted global leader in biomass sensing technologies, this sensor is now accessible to our customers through our expanding portfolio of advanced bioprocessing solutions.

What Makes OPTURA SPY® Stand Out?

• Contact-Less, Real-Time Readings
  Gain instant insights into Total Cell Concentration (TCC) and growth rates without disrupting your process or compromising sterility.

• Exceptional Accuracy at Scale
  The sensor maintains consistent performance across a wide biomass range (2–260 million cells/mL), making it ideal for batch, fed-batch, and perfusion processes.

• Proven Bubble Filter Algorithm
  Minimise signal interference with technology that actively filters out distortions from bubbles—even in highly aerated environments.

• Versatile and Easy to Use
  Thanks to its compact design and adhesive vessel adaptor, OPTURA SPY® works seamlessly with a wide variety of optically clear vessels—from benchtop bioreactors to single-use bags.

• Seamless Data Integration
  With the OPTURA SPY® HUB, users can connect to the dedicated software platform or integrate directly into existing control systems for centralised process monitoring.

The value of this technology has already been demonstrated in recent peer-reviewed research. In a 2025 study focused on Marburg Virus Glycoprotein production, scientists utilised OPTURA SPY® to enhance process control through continuous biomass insights—leading to improved nutrient feed strategies and quicker response to system changes.

Looking for a more compact format? Explore our handheld option, the OPTURA®PALM®—ideal for quick biomass checks in shake flasks, falcon tubes, and more.