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L8912 L-Leucine, Merck

L8912 Merck

L-Leucine is an essential branched-chain amino acid (BCAA) produced from non-animal sources. It is widely used in cell culture media, pharmaceutical manufacturing, and protein synthesis research.

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L-Leucine (L8912) is a high-purity, white crystalline powder that meets the requirements of the European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP), and United States Pharmacopeia (USP). As an essential amino acid, it plays a key role in protein translation via the mTOR signaling pathway and is vital for muscle protein synthesis. This product is derived from non-animal sources, making it suitable for animal-free manufacturing and research environments. It is also tested for endotoxins to ensure suitability for mammalian cell culture.

Advantages

  • Non-animal source: Suitable for use in strictly controlled animal-free manufacturing processes.
  • Pharmacopoeia Grade: Fully compliant with EP, JP, and USP testing specifications.
  • Cell Culture Tested: Verified for suitability in mammalian cell culture with endotoxin testing.
  • High Purity: Guaranteed assay range of 98.5–101.0%.
  • Multi-functional: Acts as a structural component of proteins and a signaling molecule for protein synthesis.

Technical specifications

Catalogue number L8912
Product name L-Leucine
Brand Sigma-Aldrich
CAS number 61-90-5
Assay 98.5–101.0%
Linear formula (CH3)2CHCH2CH(NH2)CO2H
Molecular weight 131.17 g/mol
Compliance EP, JP, USP
Quality Level 300
Melting point >300 °C (lit.)

Available packaging options

Container Type Pack Size
Plastic bottle 10 mg
Plastic bottle 25 g
Plastic bottle 100 g
Plastic drum 1 kg
Brand Merck